Patient counseling tool

Weight Loss Comparison Calculator

Enter a patient's height and weight to compare expected weight loss across GLP-1 medications, endoscopic sleeve gastroplasty, and bariatric surgery procedures. Results are population averages based on published trials and meta-analyses.

Patient measurements

ft
in
lb
Current BMI: 35.5
Obesity, class II
99.8 kg · 220.0 lb

Projected outcomes

Sorted by average % total body weight loss

  • Medical Weight Loss

    Phentermine

    5.0% TBWL · 12–24 weeks · Meta-analyses (monotherapy)

    −11.0 lb
    −5.0 kg · BMI → 33.7
    Projected weight: 209.0 lb (94.8 kg)
  • GLP-1

    Liraglutide (Saxenda)

    8.0% TBWL · 56 weeks · SCALE trial

    −17.6 lb
    −8.0 kg · BMI → 32.7
    Projected weight: 202.4 lb (91.8 kg)
  • Endoscopic

    Orbera Intragastric Balloon

    10.2% TBWL · 6 months · Pooled meta-analyses

    −22.4 lb
    −10.2 kg · BMI → 31.9
    Projected weight: 197.6 lb (89.6 kg)
  • GLP-1

    Semaglutide (Wegovy)

    14.9% TBWL · 68 weeks · STEP 1

    −32.8 lb
    −14.9 kg · BMI → 30.2
    Projected weight: 187.2 lb (84.9 kg)
  • Endoscopic

    Endoscopic Sleeve Gastroplasty (ESG)

    15.0% TBWL · 12 months · MERIT RCT

    −33.0 lb
    −15.0 kg · BMI → 30.2
    Projected weight: 187.0 lb (84.8 kg)
  • GLP-1

    Tirzepatide (Zepbound)

    20.9% TBWL · 72 weeks · SURMOUNT-1 (15 mg)

    −46.0 lb
    −20.9 kg · BMI → 28.1
    Projected weight: 174.0 lb (78.9 kg)
  • GLP-1

    Retatrutide (investigational)

    24.2% TBWL · 48 weeks · Phase 2 (12 mg)

    −53.2 lb
    −24.1 kg · BMI → 26.9
    Projected weight: 166.8 lb (75.6 kg)
  • Bariatric Surgery

    Sleeve Gastrectomy

    28.0% TBWL · 12–24 months · Pooled outcomes

    −61.6 lb
    −27.9 kg · BMI → 25.6
    Projected weight: 158.4 lb (71.8 kg)
  • Bariatric Surgery

    Roux-en-Y Gastric Bypass

    32.0% TBWL · 12–24 months · Pooled outcomes

    −70.4 lb
    −31.9 kg · BMI → 24.1
    Projected weight: 149.6 lb (67.9 kg)
  • Bariatric Surgery

    One Anastomosis Gastric Bypass (OAGB)

    34.0% TBWL · 12–24 months · YOMEGA & meta-analyses

    −74.8 lb
    −33.9 kg · BMI → 23.4
    Projected weight: 145.2 lb (65.9 kg)
  • Bariatric Surgery

    SADI-S

    37.0% TBWL · 12–24 months · IFSO position statement

    −81.4 lb
    −36.9 kg · BMI → 22.4
    Projected weight: 138.6 lb (62.9 kg)
  • Bariatric Surgery

    Biliopancreatic Diversion w/ Duodenal Switch

    40.0% TBWL · 12–24 months · Long-term cohorts

    −88.0 lb
    −39.9 kg · BMI → 21.3
    Projected weight: 132.0 lb (59.9 kg)

Weight loss comparison chart

Average % total body weight loss (TBWL) by intervention — sorted from least to most.

Medical Weight LossGLP-1EndoscopicBariatric Surgery

Important

Projections use average % total body weight loss reported in clinical trials and meta-analyses. Individual outcomes vary substantially based on adherence, comorbidities, metabolic factors, and operative technique. This tool is for educational discussion only and is not a substitute for clinical judgment.